Tailoring supersaturation from amorphous solid dispersions
نویسندگان
چکیده
منابع مشابه
Improved supersaturation and oral absorption of dutasteride by amorphous solid dispersions.
In this study, amorphous solid dispersions containing dutasteride and various excipients, manufactured by spray-drying processes, were characterized to determine the effects on their ability to form supersaturated solutions and to identify the effects of supersaturation on increasing the bioavailability of dutasteride. The excipients included Eudragit E, hydroxypropyl-β-cyclodextrin (HP-β-CD), ...
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ژورنال
عنوان ژورنال: Journal of Controlled Release
سال: 2018
ISSN: 0168-3659
DOI: 10.1016/j.jconrel.2018.04.014